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According to EFSA:


1.    DHA contributes to the maintenance of normal brain function
2.    EPA and DHA contribute to the normal function of the heart

 

According to EFSA, vitamin D: 

 

3.    contributes to normal absorption/utilization of calcium and phosphorus
4.    contributes to normal blood calcium levels
5.    contributes to the maintenance of normal bones
6.    contributes to the maintenance of normal muscle function
7.    contributes to the maintenance of normal teeth
8.    contributes to the normal function of the immune system
9.    has a role in the process of cell division
 

 

 

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Children need reference values based on kids – not adults

Not only are children using energy to move, they also constantly grow, develop new tissue and are under complex processes of maturation. Consequently, the amount of energy and types of nutrition needed, per kilogram body mass, is greater and different than that of an adult. This is especially true for essential fatty acids, and is the reason why a child’s fatty acids profile in blood naturally diverges from an adult’s. BalanceTest is the first Omega fatty acid measurement tool that account for these differences for children up to 10 years.

New knowledge on children’s Omega-3 index


The target Omega-3 Index for adults is ≥8%, while new research suggests that ≥6% is the optimal level for kids. 

The target Omega-3 Index for adults is ≥8% and are based on heart health indicators whereas in children, the beneficial outcomes of Omega fatty acids are measured in relation to cognition. This is because cognition is the most important developmental aspect to determine future health outcomes for the child. The most recent review on effects of Omega-3 in Children found that the most beneficial outcomes for cognition in children occur with an Omega-3 Index of ≥6% (van der Wurff et al., 2020). 

 

Omega-6 blood levels in children

 

Omega-6 is especially important during brain development and maturation.

A growing child’s Neurological health requires sufficient levels of AA (Arachidonic Acid) for the growth, repair, maintenance, and protection of neurons. Because of this crucial involvement in brain development, children naturally have a slightly higher percentage of Omega-6 levels in blood than adults. This is demonstrated in contemporary international research and confirmed in data from Zinzino’s database with over 800.000 blood tests in different age groups (See figure 1). 



Total Omega 6

Total long chain Omega-6

Aa

Dgla

0%
10%
20%
30%
40%
Children (2-10y)
Adults


Figure 1. The average n-6 AA, DGLA, %n-6 in HUFA, and total Omega-6 in children compared to adults. Note! Sample selected based on having the same level Omega-3 Index (>8), thus adjusted for age related dietary differences.   

 

BalanceTest health markers and children's threshold levels 


There is a difference between adults and children when it comes to optimal levels for each health marker in the Zinzino BalanceTest.  
As a result of the above-described metabolic growth and maturation-related differences in omega-3 and omega-6 blood status in children, all BalanceTest health markers have tailored threshold levels specific to children. For example, the Omega-6:3 ratio is naturally higher in children (5:1) than adults (3:1). Below, you can compare all thresholds levels for children and adults.



Fatty acid score

Adults
100-90%
90-50%
<50-0%
Kids
100-64%
<64-45%
<45-0%

Omega-3 indexWB*

Adults
12-8%
<8-4%
<4-0%
Kids
12-6%
<6-4%
<4-0%

Cognitive fatty acid index

Adults
0.5:1-1:1
>1:1-3:1
>3:1-6:1
Kids
0.5:1-1.5:1
>1.5:1-3:1
>3:1-6:1

Fatty acid fluidity ratio

Adults
1:1-4:1
>4:1-9:1
>9:1-25:1
Kids
1:1-6:1
>6:1-9:1
>9:1-25:1

Omega-6 (AA) levelWB*

Adults
6.5-9.5%
4.5-6.4%
9.6-12.5%
0-4.4%
12.6-25%
Kids
7-10%
4.5-6.9%
10.1-12.5%
0-4.4%
12.6-25%