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According to EFSA:


1.    DHA contributes to the maintenance of normal brain function
2.    EPA and DHA contribute to the normal function of the heart

 

According to EFSA, vitamin D: 

 

3.    contributes to normal absorption/utilization of calcium and phosphorus
4.    contributes to normal blood calcium levels
5.    contributes to the maintenance of normal bones
6.    contributes to the maintenance of normal muscle function
7.    contributes to the maintenance of normal teeth
8.    contributes to the normal function of the immune system
9.    has a role in the process of cell division
 

 

 

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Literature references

  1. Adorini, L. (2005). Intervention in autoimmunity: the potential of vitamin D receptor agonists. Cellular immunology, 233(2), 115-124. https://www.direct-ms.org/wp-content/uploads/2018/01/Adorini-intervention-05.pdf
  2. L Bishop, E., Ismailova, A., Dimeloe, S., Hewison, M., & White, J. H. (2021). Vitamin D and immune regulation: antibacterial, antiviral, anti‐inflammatory. JBMR plus, 5(1), e10405. https://scholar.google.com/scholar?hl=no&as_sdt=0%2C5&q=Vitamin+D+and+Immune+Regulation%3A+Antibacterial%2C+Antiviral%2C+Anti-Inflammatory&btnG=
  3. Bouillon, R. (2020). Vitamin D status in Africa is worse than in other continents. Lancet Glob. Health, 8, e20-e21. https://www.thelancet.com/action/showPdf?pii=S2214-109X%2819%2930492-9
  4. Bouillon, R. Comparative analysis of nutritional guidelines for vitamin D. Nat Rev Endocrinol 13, 466–479 (2017). https://doi.org/10.1038/nrendo.2017.31
  5. Burke, Louise. (2015). Nutrition for recovery after training and competition. In In L. Burke and V. Deakin (Ed.). Clinical sports nutrition 5th edition pp. 420 - 462
  6. Szu-Wen Chang, Hung-Chang Lee, (2019). Vitamin D and health - The missing vitamin in humans,
  7. Pediatrics & Neonatology, Volume 60, Issue 3, 237-244, https://doi.org/10.1016/j.pedneo.2019.04.007.
  8. Chun, R. F., Liu, P. T., Modlin, R. L., Adams, J. S., & Hewison, M. (2014). Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Frontiers in physiology, 5, 151. https://www.frontiersin.org/articles/10.3389/fphys.2014.00151/full
  9. Close, D.L. & Owens, D. (2020) The Nutrition X-change. Vitamin D. https://www.nutritionx.co.uk/wp/wp-content/uploads/2020/10/The-Nutrition-X-Change-Volume-1-Vitamin-D.pdf
  10. Crescioli, C. (2020). Vitamin D Merging into Immune System-Skeletal Muscle Network: Effects on Human Health. Applied Sciences, 10(16), 5592. https://doi.org/10.3390/app10165592
  11. Durazo-Arvizu RA, Dawson-Hughes B, Kramer H, Cao G, Merkel J, Coates PM, et al. The reverse j-shaped association between serum total 25-Hydroxyvitamin D concentration and all-cause mortality: the impact of assay standardization. Am J Epidemiol. (2017) 185:720–6. doi: 10.1093/aje/kww244
  12. EU Register on nutrition and health claims. https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/?event=search
  13. Gallagher, J. C., Yalamanchili, V., & Smith, L. M. (2013). The effect of vitamin D supplementation on serum 25OHD in thin and obese women. The Journal of steroid biochemistry and molecular biology, 136, 195-200. https://doi.org/10.1016/j.jsbmb.2012.12.003.
  14. Holick, M. F. (2007). Vitamin D deficiency. New England journal of medicine, 357(3), 266-281. https://www.nejm.org/doi/pdf/10.1056/NEJMra070553?articleTools=true
  15. Michael F. Holick, Neil C. Binkley, Heike A. Bischoff-Ferrari, Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Hassan Murad, Connie M. Weaver, (2011). Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline, The Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 7, Pages 1911–1930, https://doi.org/10.1210/jc.2011-0385
  16. Institut für Medizinizche Diagnostik Berlin – Potsdam MVZ GbR. https://www.imd-berlin.de/fileadmin/user_upload/patienteninformationen/en/Vitamin_D_EN.pdf
  17. Kheiri, B., Abdalla, A., Osman, M. et al. Vitamin D deficiency and risk of cardiovascular diseases: a narrative review. Clin Hypertens 24, 9 (2018). https://doi.org/10.1186/s40885-018-0094-4
  18. Marcinowska-Suchowierska Ewa, Kupisz-Urbańska Małgorzata, Łukaszkiewicz Jacek, Płudowski Paweł, Jones Glenville. (2018). Vitamin D Toxicity–A Clinical Perspective, Frontiers in Endocrinology (9); 550: www.frontiersin.org/article/10.3389/fendo.2018.00550. DOI=10.3389/fendo.2018.00550
  19. Mendes, M.M., Hart, K.H., Botelho, P.B. and Lanham-New, S.A. (2018), Vitamin D status in the tropics: Is sunlight exposure the main determinant?. Nutr Bull, 43: 428-434. https://doi.org/10.1111/nbu.12349
  20. Mirhosseini Naghmeh, Rainsbury Jacqueline, Kimball Samantha M. (2018). Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis; Frontiers in Cardiovascular Medicine; (5), 87. www.frontiersin.org/article/10.3389/fcvm.2018.00087. DOI=10.3389/fcvm.2018.00087     
  21. National Institutes of Health. Vitamin D. Fact sheet for health professionals. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
  22. Nordic Council of Ministers. (2014). Nordic nutrition recommendations 2012: integrating nutrition and physical activity. Nordic Council of Ministers. http://norden.diva-portal.org/smash/get/diva2:704251/FULLTEXT01.pdf
  23. Owens, D. J., Allison, R., & Close, G. L. (2018). Vitamin D and the athlete: current perspectives and new challenges. Sports medicine, 48(1), 3-16.
  24. Skrobot, A., Demkow, U., & Wachowska, M. (2018). Immunomodulatory role of vitamin D: a review. Current Trends in Immunity and Respiratory Infections, 13-23. https://doi.org/10.1007/5584_2018_246
  25. van Groningen, L., Opdenoordt, S., van Sorge, A., Telting, D., Giesen, A., & de Boer, H. (2010). Cholecalciferol loading dose guideline for vitamin D-deficient adults. European Journal of Endocrinology, 162(4), 805-811.
  26. van Schoor, N., & Lips, P. (2018). Worldwide vitamin D status. Vitamin D, 15-40. https://www.minisun.net/wp-content/uploads/pdf/vanschoor_2011.pdf
  27. Walsh, J. S., Bowles, S., & Evans, A. L. (2017). Vitamin D in obesity. Current Opinion in Endocrinology & Diabetes and Obesity, 24(6), 389-394.  https://eprints.whiterose.ac.uk/123619/3/vit%20d%20obesity%20walsh%20R1-1.pdf